UEFA club competition records - FC Twente
| Biggest home win | Result | ||
| 2012/13 | UEFA Europa League, First qualifying round |  FC Twente -
UE Santa Coloma  |
6:0 |
| 1974/75 | UEFA Cup, 1/8 Final | FC Twente -
Dukla Prague  |
5:0 |
| 1970/71 | Inter-Cities Fairs Cup, 1/16 Final | FC Twente -
Eskisehirspor  |
6:1 |
| 1973/74 | UEFA Cup, 1/16 Final | FC Twente -
Panachaiki GE  |
7:0 |
| Biggest away win | Result | ||
| 2012/13 | UEFA Europa League, Second qualifying round |  Inter Turku -
FC Twente |
0:5 |
| 1972/73 | UEFA Cup, 1/16 Final |  BK Frem -
FC Twente |
0:5 |
| Highest scoring | Result | ||
| 1970/71 | Inter-Cities Fairs Cup, 1/16 Final | FC Twente -
Eskisehirspor |
6:1 |
| 1973/74 | UEFA Cup, 1/16 Final | FC Twente -
Panachaiki GE |
7:0 |
| 1993/94 | UEFA Cup, 1/32 Final | FC Twente -
FC Bayern Munich  |
3:4 |
| Most goals in home game | Result | ||
| 2012/13 | UEFA Europa League, First qualifying round | FC Twente -
UE Santa Coloma |
6:0 |
| 1970/71 | Inter-Cities Fairs Cup, 1/16 Final | FC Twente -
Eskisehirspor |
6:1 |
| 1973/74 | UEFA Cup, 1/16 Final | FC Twente -
Panachaiki GE |
7:0 |
| Most goals in away game | Result | ||
| 2012/13 | UEFA Europa League, Second qualifying round | Inter Turku -
FC Twente |
0:5 |
| 1972/73 | UEFA Cup, 1/16 Final | BK Frem -
FC Twente |
0:5 |
| Heaviest home defeat | Result | ||
| 1974/75 | UEFA Cup, Final | FC Twente -
Borussia Moenchengladbach |
1:5 |
| Heaviest away defeat | Result | ||
| 2010/11 | UEFA Europa League, 1/4 Final |  Villarreal CF -
FC Twente |
5:1 |
| 2008/09 | UEFA Champions League, Third qualifying round |  Arsenal London -
FC Twente |
4:0 |
| 1979/80 | UEFA Cup Winners' Cup, 1/16 Final | Panionios -
FC Twente |
4:0 |
| 2008/09 | UEFA Cup, Group stage |  Paris Saint-Germain -
FC Twente |
4:0 |
Last updated on 8 September 2012
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