UEFA Europa League 2021-2022 - all matches in Knockout round play-offs
| Dates | Home | Guest | Result | ||
| 17.02.2022 |  RB Leipzig |
- |  Real Sociedad |
2:2 (1:1) | report |
| 24.02.2022 | Real Sociedad |
- | RB Leipzig |
1:3 (0:1) | report |
| 17.02.2022 |  FC Porto |
- |  SS Lazio |
2:1 (1:1) | report |
| 24.02.2022 | SS Lazio |
- | FC Porto |
2:2 (1:1) | report |
| 17.02.2022 | Sevilla FC |
- |  NK Dinamo Zagreb |
3:1 (3:1) | report |
| 24.02.2022 | NK Dinamo Zagreb |
- | Sevilla FC |
1:0 (0:0) | report |
| 17.02.2022 |  FC Sheriff Tiraspol |
- | Sporting de Braga |
2:0 (1:0) | report |
| 24.02.2022 | Sporting de Braga |
- | FC Sheriff Tiraspol |
2:0 (2:0) a.e.t.; pen. 3:2 |
report |
| 17.02.2022 | FC Barcelona |
- | Napoli |
1:1 (0:1) | report |
| 24.02.2022 | Napoli |
- | FC Barcelona |
2:4 (1:3) | report |
| 17.02.2022 | Atalanta |
- |  Olympiacos Pireaus |
2:1 (0:1) | report |
| 24.02.2022 | Olympiacos Pireaus |
- | Atalanta |
0:3 (0:1) | report |
| 17.02.2022 |  Zenit Saint Petersburg |
- | Real Betis |
2:3 (2:3) | report |
| 24.02.2022 | Real Betis |
- | Zenit Saint Petersburg |
0:0 (0:0) | report |
| 17.02.2022 | Borussia Dortmund |
- |  Rangers |
2:4 (0:2) | report |
| 24.02.2022 | Rangers |
- | Borussia Dortmund |
2:2 (1:2) | report |
Round
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