Ukrainian Premier League 2021/2022: final table of First division
| # | Club | M | W | D | L | Goal | Pts | GD | Result | |
|---|---|---|---|---|---|---|---|---|---|---|
| 1 | Shakhtar Donetsk | 18 | 15 | 2 | 1 | 49 - 10 | 47 | +39 |   Champion (Champions League) | |
| 2 | Dynamo Kiev | 18 | 14 | 3 | 1 | 47 - 9 | 45 | +38 | Vice-champion (Champions League) | |
| 3 | SC Dnipro-1 | 18 | 13 | 1 | 4 | 35 - 17 | 40 | +18 | Europa League | |
| 4 | Zarya Lugansk | 18 | 11 | 3 | 4 | 37 - 19 | 36 | +18 | Europa Conference League | |
| 5 | Vorskla Poltava | 18 | 9 | 6 | 3 | 30 - 18 | 33 | +12 | Europa Conference League | |
| 6 | PFC Olexandria | 18 | 7 | 5 | 6 | 19 - 16 | 26 | +3 | ||
| 7 | Desna Chernihiv | 18 | 7 | 4 | 7 | 22 - 27 | 25 | -5 |  Membership suspended after season | |
| 8 | Kolos Kovalivka | 18 | 7 | 3 | 8 | 14 - 23 | 24 | -9 | ||
| 9 | Veres Rovno | 18 | 6 | 5 | 7 | 15 - 20 | 23 | -5 | ||
| 10 | Metalist 1925 | 18 | 6 | 1 | 11 | 17 - 29 | 19 | -12 | ||
| 11 | Rukh Lviv | 17 | 4 | 6 | 7 | 16 - 21 | 18 | -5 | ||
| 12 | FC Lviv | 18 | 4 | 5 | 9 | 14 - 30 | 17 | -16 | ||
| 13 | Chernomorets Odessa | 18 | 3 | 5 | 10 | 20 - 40 | 14 | -20 | ||
| 14 | Inhulets Petrove | 17 | 3 | 4 | 10 | 13 - 28 | 13 | -15 | ||
| 15 | FC Mynai | 18 | 1 | 7 | 10 | 12 - 30 | 10 | -18 | ||
| 16 | FC Mariupol | 18 | 2 | 2 | 14 | 21 - 44 | 8 | -23 | Membership suspended after season | |
| Pts = Points M = Matches played; W = Matches won; D = Matches drawn; L = Matches lost; GD = Goal difference; | ||||||||||
Notes:
- Champion
 - national cup holder
- participation in European competition
 - promoted
- relegated
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2020/2021
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