UEFA Champions League 2021-2022 - all matches in Round of 16
| Dates | Home | Guest | Result | ||
| 23.02.2022 |  SL Benfica |
- |  Ajax Amsterdam |
2:2 (1:2) | report |
| 15.03.2022 | Ajax Amsterdam |
- | SL Benfica |
0:1 (0:0) | report |
| 22.02.2022 |  Chelsea FC |
- |  Lille OSC |
2:0 (1:0) | report |
| 16.03.2022 | Lille OSC |
- | Chelsea FC |
1:2 (1:1) | report |
| 15.02.2022 | Sporting CP |
- | Manchester City FC |
0:5 (0:4) | report |
| 09.03.2022 | Manchester City FC |
- | Sporting CP |
0:0 (0:0) | report |
| 16.02.2022 |  Inter Milan |
- | Liverpool FC |
0:2 (0:0) | report |
| 08.03.2022 | Liverpool FC |
- | Inter Milan |
0:1 (0:0) | report |
| 16.02.2022 |  Red Bull Salzburg |
- |  FC Bayern Munich |
1:1 (1:0) | report |
| 08.03.2022 | FC Bayern Munich |
- | Red Bull Salzburg |
7:1 (4:0) | report |
| 23.02.2022 |  Atletico Madrid |
- | Manchester United |
1:1 (1:0) | report |
| 15.03.2022 | Manchester United |
- | Atletico Madrid |
0:1 (0:1) | report |
| 15.02.2022 | Paris Saint-Germain |
- | Real Madrid |
1:0 (0:0) | report |
| 09.03.2022 | Real Madrid |
- | Paris Saint-Germain |
3:1 (0:1) | report |
| 22.02.2022 | Villarreal CF |
- | Juventus |
1:1 (0:1) | report |
| 16.03.2022 | Juventus |
- | Villarreal CF |
0:3 (0:0) | report |
Round
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